Chromatin self-organization by mutation bias.
Chromatin self-organization by mutation bias.
复制标题
通过突变偏差进行染色质自组织。
DOI：
10.1007/bf00173411
复制
发表时间：
1994
影响因子：
3.9
通讯作者：
Holmquist,GP
中科院分区：
文献类型：
--
作者：
Holmquist,GP
Proteins, on binding to a DNA sequence, alter the frequency and quality of mutations that occur in the sequence. This represents a reverse flow of information from proteins to DNA. Nucleosome binding causes patterns of UV-induced damage which, when converted to mutations by replication, will phase nucleosomes. We propose that DNA binding proteins create their own high- or low-affinity binding sites along DNA sequences by biased mutational pressure.
