Secondhand smoke exposure and hair nicotine in children: age-dependent differences.
Secondhand smoke exposure and hair nicotine in children: age-dependent differences.
复制标题
儿童二手烟暴露和头发尼古丁：年龄依赖性差异。
DOI：
10.1093/ntr/ntr269
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发表时间：
2012
期刊：
影响因子：
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通讯作者：
Bauer,JohnA
中科院分区：
文献类型：
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作者：
Groner,JudithA;Huang,Hong;Nicholson,Lisa;Kuck,Jennifer;Boettner,Bethany;Bauer,JohnA
在美国，相当大比例的儿童仍然暴露于二手烟（SHS）。我们报告了在两组儿童（2-5岁和9-14岁）中观察到的父母报告其孩子的SHS暴露之间的关系，这些儿童具有长期SHS暴露的生物学标记，即头发尼古丁。方法采用方便抽样的方法，选取2-5岁和9-14岁两个年龄组的健康儿童作为研究对象。通过问卷调查和头发取样来评估SHS暴露的存在和量。结果共招募115名参与者（54名幼儿和61名青少年）。这两组在人口统计和报告的SHS暴露方面相似。头发中的尼古丁含量因年龄的不同而有显著差异，幼儿的含量高于青少年。头发尼古丁最重要的独立决定因素是幼儿年龄组，接受医疗保险的医疗补助，以及受试者在24小时内接触的吸烟者数量。我们的研究结果表明，与年龄较大的人群相比，参加医疗补助计划的幼儿的头发尼古丁水平更高，这是一种暴露于SHS的生物标志物。有必要进一步努力保护这一弱势群体，降低他们一生中暴露于二手烟相关疾病的风险。
IntroductionA significant proportion of children in the United States remain exposed to secondhand smoke (SHS). We are reporting on relationships observed between parental report of their child’s SHS exposure in two groups of children (ages 2–5 years and 9–14 years) with a biological marker of long-term SHS exposure, hair nicotine.MethodsParticipants were healthy children recruited via convenience sampling for two age groups: 2–5 years and 9–14 years. The presence and amount of SHS exposure were assessed by both questionnaire and hair sampling for nicotine determination.ResultsA total of 115 participants were recruited (54 toddlers and 61 youth). The groups were similar in terms of demographics and reported SHS exposure. Hair nicotine levels were significantly different by age group, with toddlers having higher levels than youth. The most important independent determinants of hair nicotine were toddler age group, receiving Medicaid for health insurance, and number of smokers the subject was exposed to in 24 hr.ConclusionsOur findings suggest that young children who are insured by Medicaid have higher levels of hair nicotine, a biomarker of SHS exposure, when compared with an older age group. Further efforts to protect this vulnerable population and mitigate their lifetime risks of SHS exposure–related morbidities are warranted.