Diabetic Patients Have an Increased Risk of Vertebral Fractures Independent of BMD or Diabetic Complications
Diabetic Patients Have an Increased Risk of Vertebral Fractures Independent of BMD or Diabetic Complications
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DOI：
10.1359/jbmr.081207
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发表时间：
2009-04-01
影响因子：
6.2
通讯作者：
Sugimoto, Toshitsugu
中科院分区：
文献类型：
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作者：
Yamamoto, Masahiro;Yamaguchi, Toru;Sugimoto, Toshitsugu
尽管2型糖尿病(T2 DM)患者髋部骨折的风险增加，但脊椎骨折(VF)的风险及其与BMD的相关性仍不清楚。我们对日本T2 DM患者(男性16 1例，年龄50岁，绝经后女性137例)和非糖尿病对照组(分别为76例和622例)进行了腰椎侧位X线片和腰椎(L)、股骨颈(FN)和桡骨(R)的DXA检查。经年龄、体重指数和L骨密度校正后的Logistic回归分析显示，T2 DM是女性(OR=1.86，p=0.019)和男性(OR=4.73，p
Although patients with type 2 diabetes (T2DM) have an increased risk of hip fracture, risk of vertebral fracture (VF) and its association with BMD are still unclear. We examined Japanese T2DM patients (161 men >50 yr and 137 postmenopausal women) and non-DM controls (76 and 622, respectively) by lateral spine radiography and DXA at the lumbar spine (L), femoral neck (FN), and radius (R). Logistic regression analysis adjusted for age, body mass index, and L-BMD showed that the presence of T2DM was an independent risk factor for prevalent VFs in women (OR=1.86, p=0.019) and men (OR=4.73, p