Pyrrocidines A and B, new antibiotics produced by a filamentous fungus
Pyrrocidines A and B, new antibiotics produced by a filamentous fungus
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DOI：
10.1016/s0040-4039(02)00099-0
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发表时间：
2002-02-25
影响因子：
1.8
通讯作者：
Carter, GT
中科院分区：
文献类型：
--
作者：
He, HY;Yang, HY;Carter, GT
从真菌LL-Cyan426发酵液中分离到两种含有罕见13元大环的新型抗生素pyrorocidines A(1)和B(2)。吡啶A(1)对革兰氏阳性菌（包括耐药菌株）具有强效活性。用光谱方法确定了这些化合物的结构。(C) 2002 Elsevier Science Ltd.版权所有。
Pyrrocidines A (1) and B (2), two new antibiotics, containing rare 13-membered macrocycles, were isolated from the fermentation broth of a fungus, LL-Cyan426. Pyrrocidine A (1) exhibited potent activity against Gram-positive bacteria, including drug-resistant strains. The structures of these compounds were established using spectroscopic methods. (C) 2002 Elsevier Science Ltd. All rights reserved.