Reasons for increasing trends in large for gestational age births
Reasons for increasing trends in large for gestational age births
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DOI：
10.1097/01.aog.0000141442.59573.cd
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发表时间：
2004-10-01
影响因子：
7.2
通讯作者：
Cnattingius, S
中科院分区：
文献类型：
--
作者：
Surkan, PJ;Hsieh, CC;Cnattingius, S
目的：描述足月和足月后比例的变化幅度（37周或以上）大于胎龄儿（LGA）的出生率的时间趋势是否可以用母体危险因素的变化来解释。方法：使用基于人口的瑞典出生登记，我们分析了从1992年到2001年的出生数据的妇女谁交付活的，单胎，足月婴儿无畸形（N = 874,163）。无条件Logistic回归模型的几率LGA birth.RESULTS：平均出生体重和比例的LGA出生和出生4,500克或以上上升，在1992年至2001年期间。未经调整的分析估计，LGA出生的风险在10年内增加了23%。然而，超重和肥胖（身体质量指数25或更高）的流行率从25%上升到36%，而吸烟的流行率在同一时期从23%下降到11%。调整后的趋势，同时在所有协变量，LGA出生和日历年之间的关联disappeared.CONCLUSION：LGA出生的比例随着时间的推移增加的解释是同时增加的母亲体重指数和减少母亲吸烟。随着青少年和年轻女性超重患病率的增加，LGA婴儿的患病率和相关风险可能会随着时间的推移而增加。((C)2004年由美国妇产科医师学会。
OBJECTIVE: To describe the magnitude of change in the proportion of term and postterm (37 completed weeks or more) large for gestational age (LGA) infants between 1992-2001 in Sweden and to examine whether time trends in prevalence of LGA births can be explained by changes in maternal risk factors.METHODS: Using the population-based Swedish Birth Register, we analyzed data from 1992 through 2001 on births of women who delivered live, singleton, term infants without malformations (N = 874,163). Unconditional logistic regression was used to model the odds of LGA birth.RESULTS: Mean birth weight and proportions of LGA births and births 4,500 g or more rose during the period 1992 to 2001. An unadjusted analysis estimated that the risk of LGA birth increased by 23% over 10 years. However, the prevalence of overweight and obesity (body mass index of 25 or greater) increased from 25% to 36%, and the prevalence of smoking decreased from 23% to 11% during the same period. After adjusting trends in all covariates simultaneously, the association between risk of LGA birth and calendar year disappeared.CONCLUSION: The increasing proportions of LGA births over time is explained by concurrent increases in maternal body mass index and decreases in maternal smoking. With the increasing prevalence of overweight among adolescents and young women, the prevalence of LGA infants and associated risks may increase over time. ((C) 2004 by The American College of Obstetricians and Gynecologists.).