Assessment of intra-individual variation in prostate-specific antigen levels in a biennial randomized prostate cancer screening program in Sweden
Assessment of intra-individual variation in prostate-specific antigen levels in a biennial randomized prostate cancer screening program in Sweden
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DOI：
10.1002/pros.20286
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发表时间：
2005-11-01
期刊：
影响因子：
2.8
通讯作者：
Christensson, A
中科院分区：
文献类型：
--
作者：
Bruun, L;Becker, C;Christensson, A
背景前列腺特异性抗原（PSA）测量值的变异程度对于解释筛查项目中的检测结果，特别是解释重复检测之间变化的意义非常重要。本研究旨在确定健康男性PSA的长期个体内变异。随机选择1995-1996年至2001-2002年在瑞典进行的两年期前列腺癌筛查项目（ERSPC）中的男性队列。我们研究了总PSA（tPSA）水平
BACKGROUND. The degree of variability in prostate-specific antigen (PSA) measurements isimportant for interpreting test results in screening programs, and particularly for interpreting the significance of changes between repeated tests. This study aimed to determine the long-term intra-individual variation for PSA in healthy men.METHODS. A randomly selected cohort of men in a biennial prostate cancer screening program (ERSPC) conducted in Sweden from 1995-1996 to 2001-2002. We studied men who had total PSA (tPSA) levels