The Flannotator-a gene and protein expression annotation tool for Drosophila melanogaster
The Flannotator-a gene and protein expression annotation tool for Drosophila melanogaster
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DOI：
10.1093/bioinformatics/btp012
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发表时间：
2009-02-15
期刊：
影响因子：
5.8
通讯作者：
Russell, S.
中科院分区：
文献类型：
--
作者：
Ryder, E.;Spriggs, H.;Russell, S.
了解发育过程和建立一体化系统生物学需要详细的时空表达的基因和蛋白质的知识。我们已经开发了一个软件包，用于收集，存储和搜索果蝇蛋白质或基因表达模式的注释。使用标准的果蝇解剖学和基因本体论，该系统可以很容易地捕获在任何发育阶段和所有公认的组织类型以及亚细胞定位的细节的表达模式。基于网络的系统允许多个组协作并共享图像和注释。
Understanding developmental processes and building towards integrative systems biology require detailed knowledge of the spatio-temporal expression of genes and proteins. We have developed a software package for collecting, storing and searching the annotation of protein or gene expression patterns in Drosophila melanogaster. Using standard Drosophila anatomy and Gene Ontologies, the system can readily capture expression patterns at any stage of development and in all recognized tissue types as well as details of sub-cellular localization. The web-based system allows multiple groups to work in collaboration and share images and annotation.