Mild and convenient one pot synthesis of N-hydroxyimides from N-unsubstituted imides
Mild and convenient one pot synthesis of N-hydroxyimides from N-unsubstituted imides
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DOI：
10.1081/scc-100103264
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发表时间：
2001-01-01
影响因子：
2.1
通讯作者：
Marcadal-Abbadi, C
中科院分区：
文献类型：
--
作者：
Einhorn, C;Einhorn, J;Marcadal-Abbadi, C
本文介绍了一种由N-未取代酰亚胺一锅法合成各种N-羟基酰亚胺的新方法。酰亚胺首先转化为它们的N-Boc衍生物，然后与羟胺水溶液反应，得到相应N-羟基酰亚胺的结晶羟铵盐。过滤和酸性后处理得到纯N-羟基酰亚胺。
A new, one pot synthesis of various N-hydroxyimides from N-unsubstituted imides is described. Imides are first transformed into their N-Boc derivatives, which are next reacted with aqueous hydroxylamine, providing crystalline hydroxylammonium salts of the corresponding N-hydroxyimides. Filtration and acidic workup affords pure N-hydroxyimides.