Effectiveness of first eight methadone maintenance treatment clinics in China
Effectiveness of first eight methadone maintenance treatment clinics in China
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DOI：
10.1097/01.aids.0000304704.71917.64
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发表时间：
2007-12-01
期刊：
影响因子：
3.8
通讯作者：
Wu, Zunyou
中科院分区：
文献类型：
--
作者：
Pang, Lin;Hao, Yang;Wu, Zunyou
目的：评价中国8家美沙酮维持治疗（MMT）诊所一期疗效。设计：重复横断面调查。方法：在入组时、入组后6个月和12个月，对8家MMT诊所第一阶段的患者进行3次调查。比较了三个时期的吸毒行为、与毒品有关的犯罪活动以及与家庭的关系。每个病人在入院时采集血样并进行艾滋病毒检测，艾滋病毒阴性的病人在12个月后重新进行检测。结果：第一、二、三次调查分别有585名、609名和468名客户参与。三次调查发现，吸毒客户比例从69.1下降到8.9和8.8%，近一个月注射次数从每月90次下降到每月2次，就业人数从22.9%上升到43.2和40.6%，自述犯罪行为从20.7%下降到3.6和3.8%。到第三次调查时，65.8%的来访者反映与家庭的关系和谐，比进入时的46.8%有所增加，95.9%的来访者对MMT服务感到满意。在12个月内，在1153名客户中发现了8例HIV血清转化。结论：研究表明，第一阶段的MMT有助于减少毒品使用、毒品注射行为、毒品相关犯罪行为、艾滋病毒感染，并改善参与MMT方案的海洛因使用者的家庭关系。MMT需要在全国范围内迅速扩大，并改善服务。(c) 2007年威科医疗-利平科特·威廉姆斯和威尔金斯。
Objective: To evaluate the effectiveness of the first phase of eight methadone maintenance treatment (MMT) clinics in China.Design: Repeated cross-sectional surveys.Methods: Three surveys of clients attending the first phase of eight MMT clinics were carried out at entry, and 6 and 12 months after enrolment. Drug using behaviours, drug- related criminal activity, and relationships with families were compared for the three periods. Blood specimen were collected and tested for HIV for each client at entry, and HIV-negative clients were re-tested after 12 months.Results: A total of 585, 609 and 468 clients participated in the first, second and third surveys, respectively. The proportion of clients who injected drugs reduced from 69.1 to 8.9 and 8.8%, and the frequency of injection in the past month had reduced from 90 times per month to twice per month, employment increased from 22.9 to 43.2 and 40.6%, and self-reported criminal behaviours reduced from 20.7 to 3.6 and 3.8% in the three surveys. By the third survey, 65.8% of clients reported a harmonious relationship with families, an increase from 46.8% at entry, and 95.9% of clients were satisfied with MMT services. Eight HIV seroconversions were found among 1153 clients during 12 months.Conclusion: The study demonstrated that the first phase MMT contributed to a reduction in drug use, drug injecting behaviours, drug-related criminal behaviours, HIV infections, and improved relationships within families among heroin users who participated in the MMT programme. MMT needs to be scaled up nationwide rapidly with improved services. (c) 2007 Wolters Kluwer Health-Lippincott Williams & Wilkins.