The sensory system: More than just a window to the external world.
The sensory system: More than just a window to the external world.
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DOI：
10.1080/19420889.2015.1017159
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发表时间：
2015-03
影响因子：
--
通讯作者：
Pletcher SD
中科院分区：
文献类型：
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作者：
Gendron CM;Chung BY;Pletcher SD
虽然感官系统的传统重要性在于其感知外界信息的能力，但新发现表明，感官知觉对健康和寿命的影响比以前所认识的要大。这些效应在物种间是保守的。在这篇小综述中，我们讨论了已经确定的显著影响生物体生理和寿命的特定感官线索。在衰老领域正在进行的工作已经开始确定介导感官信号广泛影响的下游分子。候选药物包括FOXO、神经肽F （NPF）、脂肪动力学激素（AKH）、多巴胺、血清素和章鱼胺。然后，我们讨论了从我们目前对感官知觉对健康和寿命的影响的理解中产生的许多含义。
While the traditional importance of the sensory system lies in its ability to perceive external information about the world, emerging discoveries suggest that sensory perception has a greater impact on health and longevity than was previously appreciated. These effects are conserved across species. In this mini-review, we discuss the specific sensory cues that have been identified to significantly impact organismal physiology and lifespan. Ongoing work in the aging field has begun to identify the downstream molecules that mediate the broad effects of sensory signals. Candidates include FOXO, neuropeptide F (NPF), adipokinetic hormone (AKH), dopamine, serotonin, and octopamine. We then discuss the many implications that arise from our current understanding of the effects of sensory perception on health and longevity.