Comments regarding the American Association of Directors of Anatomic and Surgical Pathology (ADASP) recommendations for the reporting of urinary bladder specimens containing bladder neoplasms: Comparison with the Japanese General Rule for Clinical and Pathological Studies on Bladder Cancer

Comments regarding the American Association of Directors of Anatomic and Surgical Pathology (ADASP) recommendations for the reporting of urinary bladder specimens containing bladder neoplasms: Comparison with the Japanese General Rule for Clinical and Pathological Studies on Bladder Cancer
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关于美国解剖和外科病理学主任协会 (ADASP) 关于报告含有膀胱肿瘤的膀胱标本的建议的评论:与日本膀胱癌临床和病理研究一般规则的比较

DOI:
10.1111/j.1440-1827.1997.tb04503.x
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发表时间:
1997
期刊:
Pathology international (Print)
影响因子:
--
通讯作者:
K. Kishi
K. Kishi
中科院分区:
--
文献类型:
--
作者:
K. Kishi

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The American Association of Directors of Anatomic and Surgical Pathology’s (ADASP) reporting system of urinary bladder specimen containing bladder neoplasms is closely similar to the General Rule for Clinical and Pathological Studies on Bladder Cancer‘ by the Japanese Urological Association and The Japanese Society of Pathology, except for several of their new proposals. The Japanese histological grading of transitional cell carcinoma (TCC) is in accordance with the World Health Organization (WHO) classification? On the other hand, in Murphy’s grading system, TCC of the bladder is divided into two categories; low grade (well differentiated) and high grade (moderately to poorly differentiated)? Low grade TCC in Murphy’s classification corresponds to papilloma or grade 1 tumor in WHO, and likewise for high grade TCC to grade 3 tumor. The ADASP state that many tumors classed as grade 2 in WHO would be considered as high grade in Murphy’s classification. In contrast to low grade TCC, almost all high grade tumors in Murphy’s classification have aneuploid DNA while blood group antigen expression (ABH, Lewis a, b and X and Themsen-Friedenreich) is absent or abnormal in approximately 90%. One of the ADASP’s newest observations is the existence of wispy smooth muscle fiber in lamina propria, reminiscent of a muscularis mucosa. They point out that well-developed muscularis mucosa occur in less than 5% of human urinary bladders, and thus the correct identification of these wispy fibers is important for the accurate pathologic staging of bladder neoplasms. Pagetoid variant of carcinoma in situ (CIS) in urothelial