Contagious equine metritis: effect of vaccination on control of the disease.
Contagious equine metritis: effect of vaccination on control of the disease.
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传染性马子宫炎：疫苗接种对控制疾病的作用。
DOI：
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发表时间：
1981
影响因子：
1
通讯作者：
Sahu Sp
中科院分区：
文献类型：
--
作者：
Sahu Sp
通过静脉注射、皮下注射和宫内注射（或这些途径的组合）给小马接种灭活的传染性马子宫炎（CEM）细菌。接种后血清凝集抗体滴度为1:64 ~ 1:10 . 24。经IU途径培养96 h的小马驹感染CEM细菌，可出现CEM的临床症状，但接种疫苗的母马的症状较未接种疫苗的母马轻。该细菌是在攻毒后从母马的分泌物和子宫样本中分离出来的。通过凝集试验（平板、试管和抗球蛋白）和酶联免疫吸附试验，观察到感染母马对CEM细菌的低滴度IU抗体。而被动血凝试验可获得较高的抗体效价。
Pony mares were vaccinated with killed contagious equine metritis (CEM) bacteria by IV, subcutaneous, and intrauterine (IU) routes (or a combination of these routes). The serum agglutinating antibody titer varied from 1:64 to 1:1,024 after vaccination. In pony mares challenge exposed with 96-hour-old culture of CEM bacteria given by IU route, there were clinical signs of CEM, but these signs were less severe in vaccinated mares than in nonvaccinated mares. The bacterium was isolated for the exudate and from uterine samples collected from the mares after challenge exposure. A low titer of IU antibodies to CEM bacteria in infected mares was observed with agglutination tests (plate, tube, and antiglobulin), and enzyme-linked immunosorbent assay. However, a high antibody titer was obtained when passive hemagglutination test was used.