Neural and Mechanical Contributions to the Stretch Reflex: A Model Synthesis
Neural and Mechanical Contributions to the Stretch Reflex: A Model Synthesis
复制标题
神经和机械对牵张反射的贡献：模型综合
DOI：
10.1114/1.1432692
复制
发表时间：
2004
影响因子：
3.8
通讯作者：
P. Crago
中科院分区：
文献类型：
--
作者：
Chou;P. Crago
摘要利用两种本体感受器（肌纺锤体和高尔基肌腱器官）及其相关传入神经（Ia、II和Ib）、α运动神经元池及其反射通路、α运动神经元向束内肌（β神经支配）和束外肌的分支等神经和肌肉组分的模型，合成了脱脑猫比目鱼肌牵张反射模型。肌肉和受体模型的参数是独立选择的，以匹配它们在隔离状态下的反应。估计反射增益和γ输入与Nichols和Houk测量的拉伸反应相吻合。所选择的反射增益和γ输入并不是唯一的；许多不同的组合再现了典型的拉伸反应。该模型使用一组固定参数，预测了拉伸反射的许多力学特性，包括线性化效应（当拉伸幅度和方向发生变化时），以及对操作力和初始肌肉长度的依赖。由于外挤压肌模型失效，该模型不能准确预测高拉伸速度下的反应。©2002生物医学工程学会。
AbstractA model for the soleus stretch reflex in the decerebrate cat was synthesized from models of the neural and muscular components, including the two proprioceptors (the muscle spindle and Golgi tendon organ) and their associated afferents (Ia, II, and Ib), the α motoneuron pool with its reflex pathways, the branches of the α motoneurons to the intrafusal muscles (β innervation), and the extrafusal muscle. Parameters for the muscle and receptor models were chosen independently to match their responses in isolation. Reflex gains and γ inputs were estimated to fit the response to stretch measured by Nichols and Houk. The chosen reflex gains and γ inputs are not unique; many different combinations reproduced the characteristic stretch response. With a single set of fixed parameters, the model predicted many mechanical properties of the stretch reflex, including linearization effects (when the stretch magnitude and direction are varied), as well as the dependence on operating force and initial muscle length. The model did not accurately predict the responses at higher stretch velocities, due to failure of the extrafusal muscle model. © 2002 Biomedical Engineering Society.
PAC02: 8719Ff, 8719Rr, 8719La
猫比目鱼肌和胫前屈肌之间异质抑制的机械分析。
影响因子：
2.5
作者：
Nichols,TR;Koffler-Smulevitz,D
通讯作者：
Koffler-Smulevitz,D