Rapid versus standard testing for prenatal HIV screening in a predominantly Hispanic population
Rapid versus standard testing for prenatal HIV screening in a predominantly Hispanic population
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DOI：
10.1038/jp.2009.122
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发表时间：
2010-01-01
影响因子：
2.9
通讯作者：
Levison, J.
中科院分区：
文献类型：
--
作者：
Tung, C. S.;Sangi-Haghpeykar, H.;Levison, J.
目的：本研究的目的是检查的OraQuick快速人类免疫缺陷病毒（HIV）检测的假阳性率相比，ELISA检测在怀孕患者的低socioeconomic status.Study设计：从2005年2月10日和2005年6月1日之间收集的孕妇的血液样本进行了测试与HIV ELISA和OraQuick快速HIV检测。结果：910例患者中，14例（1.5%）HIV ELISA检测阳性，仅5例确诊为HIV。ELISA检测的阳性预测值为35.7%，而100%的OraQuick快速test.Conclusion：在一个主要是低社会经济的西班牙裔患者人群中，0.5%的艾滋病毒感染率，假阳性艾滋病毒检测是较低的OraQuick快速HIV检测与HIV ELISA检测。实施艾滋病毒快速检测将减轻与艾滋病毒假阳性检测相关的情绪困扰和不必要的分娩期和新生儿齐多夫定治疗。Journal of Perinatology（2010）30，30-32; doi：10.1038/jp.2009.122; 2009年9月10日在线发表
Objective: This study aimed to examine the false positive rate of the OraQuick rapid human immunodeficiency virus (HIV) test compared with the ELISA test in pregnant patients of low socioeconomic status.Study Design: Blood samples from pregnant patients collected between 10 February 2005 and 1 June 2005 were tested with HIV ELISA and OraQuick rapid HIV tests. The positive predictive values of both tests were calculated.Result: Of 910 patients, 14 (1.5%) patients had a positive HIV ELISA test, with only 5 patients confirmed for HIV. The positive predictive value for the ELISA test was 35.7% compared with 100% for the OraQuick rapid test.Conclusion: In a predominantly low socioeconomic Hispanic patient population with a 0.5% HIV prevalence, false positive HIV testing is lower for the OraQuick rapid HIV test compared with the HIV ELISA test. Implementation of the rapid HIV test would mitigate the emotional distress and unnecessary intrapartum and neonatal zidovudine treatments associated with false positive HIV testing. Journal of Perinatology (2010) 30, 30-32; doi: 10.1038/jp.2009.122; published online 10 September 2009