Survivorship science at the National Institutes of Health 2017-2021
Survivorship science at the National Institutes of Health 2017-2021
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DOI：
10.1007/s11764-023-01414-0
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发表时间：
2023-06-10
影响因子：
3.7
通讯作者：
Tonorezos, Emily
中科院分区：
文献类型：
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作者：
Mollica, Michelle A.;Tesauro, Gina;Tonorezos, Emily
目的描述美国国立卫生研究院（NIH）癌症生存赠款在过去5年中资助的特点，并确定未来努力和倡议的差距领域。方法研究项目赠款（RPG）在2017年至2021年财政年度（FY）期间资助的癌症生存，使用文本挖掘算法从NIH研究，条件，和疾病分类（RCDC）词库与生存相关的条款。对每个赠款的标题、摘要、具体目标和公共卫生相关性部分进行了资格审查。符合资格标准的赠款被双重编码以提取研究特征（例如，从2017财年到2021财年，14个NIH研究所共资助了586笔赠款，每个财年新资助的赠款数量都在增加，从2017年的68笔增加到2021年的105笔。大约60%的赠款包括干预研究，干预措施通常集中在心理社会或支持性护理（32.0%）。赠款最常见的主要重点是癌症治疗的晚期和长期效果（46.6%），最不经常的财政困难。结论这个组合分析的结果表明，在过去五年中，赠款的数量和广度的总体增长，对癌症幸存者的影响对目前NIH赠款的审查表明，需要扩大研究，以了解和解决幸存者需要确保美国超过1800万癌症幸存者拥有最佳的生活质量和健康结果。
PurposeTo describe the characteristics of National Institutes of Health (NIH) cancer survivorship grants funded over the past 5 years and identify gap areas for future efforts and initiatives.MethodsResearch project grants (RPG) funded during Fiscal Year (FY) 2017 to 2021 focused on cancer survivorship were identified using a text mining algorithm of words from the NIH Research, Condition, and Disease Categorization (RCDC) thesaurus with survivorship-relevant terms. The title, abstract, specific aims, and public health relevance section of each grant were reviewed for eligibility. Grants meeting the eligibility criteria were double coded to extract study characteristics (e.g., grant mechanism, study design, study population).ResultsA total of 586 grants were funded by 14 NIH Institutes from FY2017 to FY2021, and the number of newly funded grants increased each FY, from 68 in 2017 to 105 in 2021. Approximately 60% of all grants included an intervention study, and interventions most often focused on psychosocial or supportive care (32.0%). The most common primary focus of the grants was late- and long-term effects of cancer treatment (46.6%), and least often financial hardship.ConclusionsThe results of this portfolio analysis indicate overall growth in the number and breadth of grants over the last five years, although notable gaps persist.Implications for Cancer SurvivorsThis review of current NIH grants suggests a need for expanded research to understand and address survivor needs to ensure that the over 18 million cancer survivors in the United States have optimal quality of life and health outcomes.