Dietary conjugated linoleic acids alter adipose tissue and milk lipids of pregnant and lactating sows
Dietary conjugated linoleic acids alter adipose tissue and milk lipids of pregnant and lactating sows
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DOI：
10.1093/jn/130.9.2292
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发表时间：
2000-09-01
影响因子：
4.2
通讯作者：
Bee, G
中科院分区：
文献类型：
--
作者：
Bee, G
共轭亚油酸（CLA）已被证明会影响各种组织中脂肪酸的合成。本研究的目的是比较商业来源的CLA与富含亚油酸的油（LA），提供给12个经产母猪在妊娠期和哺乳期，对脂肪组织和牛奶脂肪酸组成的影响。在共轭亚油酸油中检测到的共轭亚油酸异构体为（按数量级）c9，t11; t10，c12; c9，c11; t9，t11/t10，t12和c10，c12，总量为58.9 g/100 g脂肪。在妊娠第7天和第97天从背膘中进行活检，并在分娩后第2、9、16和23天收集乳汁样品。对于上午分娩的母猪，在1100 h采集初乳和成熟乳样品，对于下午分娩的母猪，在1500 h采集初乳和成熟乳样品。补充剂中的所有主要CLA异构体都转移到组织和乳脂中，与LA组相比，组织和乳汁中的饱和脂肪酸水平显着增加，单不饱和脂肪酸水平显着降低。这些发现表明，CLA在从头脂肪酸合成和去饱和过程中的脂肪组织和乳腺的明显参与。膳食CLA异构体的估计转移效率为41-52%的背膘和55-69%的成熟牛奶。掺入和摄取效率似乎是选择性的，对于c9，t11-CLA发现最高值。总体而言，妊娠期和哺乳期母猪日粮中添加CLA显著改变了背膘和乳脂肪酸组成。
Conjugated linoleic acids (CLA) have been shown to affect fatty acid synthesis in various tissues. The objective of the study was to compare the effect of a commercial source of CLA with a linoleic acid-enriched oil (LA), supplied to 12 multiparous sows during gestation and lactation, on adipose tissue and milk fatty acid composition. The CLA isomers detected in the CLA oil were (in order of magnitude) c9,t11; t10,c12; c9,c11; t9,t11/t10,t12 and c10,c12 and amounted to 58.9 g/100 g fat. Biopsies were taken from the backfat on d 7 and 97 of gestation and milk samples were collected on d 2, 9, 16 and 23 after farrowing. Collection of colostrum and mature milk samples took place at 1100 h for sows who farrowed in the morning or at 1500 h for those who farrowed in the afternoon. All major CLA isomers in the supplement were transferred to the tissue and milk fat and, compared with the LA group, significantly increased saturated fatty acid and decreased monounsaturated fatty acid levels in the tissue and milk. These findings suggest a distinct involvement of CLA in the de novo fatty acid synthesis and desaturation process in the adipose tissue and mammary gland. Estimated transfer efficiency of dietary CLA isomers was 41-52% for the backfat and 55-69% for the mature milk. The incorporation and uptake efficiency seemed to be selective with the highest values found for c9,t11-CLA. Overall, dietary CLA supplementation of sows during gestation and lactation markedly altered backfat and milk fatty acid composition.