METHYLATION STATUS OF INTRACELLULAR DENGUE TYPE-2 40-S RNA
METHYLATION STATUS OF INTRACELLULAR DENGUE TYPE-2 40-S RNA
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DOI：
10.1016/0042-6822(79)90181-8
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发表时间：
1979-01-01
期刊：
影响因子：
3.7
通讯作者：
DUBIN, DT
中科院分区：
文献类型：
--
作者：
CLEAVES, GR;DUBIN, DT
检测登革2型黄病毒细胞内40 S RNA的甲基化状态。该RNA每个分子含有m7 G（5“）ppp（5”）ppp形式的单个I型帽。不到1/5的分子在帽或内部含有腺嘌呤碱基甲基化。[非洲绿色猴肾] Vero宿主细胞poly A+ RNA含有I型和II型帽和内部N6-甲基腺嘌呤。登革病毒甲基化和宿主RNA和其他mRNA之间的差异可能产生的影响进行了讨论。
The methylation status of the dengue-2 flavivirus intracellular 40 S RNA was examined. This RNA contained a single type I cap per molecule of the form m7G(5'')ppp(5'')Amp. Less than 1 molecule in 5 contained adenine base methylation either in the cap or internally. The [African green monkey kidney] Vero host cell poly A+ RNA contained both types I and II caps and internal N6-methyladenine. Possible implications of the differences between dengue virus methylation and that of the host RNA and other mRNA are discussed.