POPULATION-DYNAMICS OF TRICHOSTRONGYLUS-COLUBRIFORMIS IN SHEEP - THE EFFECT OF HOST AGE ON THE ESTABLISHMENT OF INFECTIVE LARVAE
POPULATION-DYNAMICS OF TRICHOSTRONGYLUS-COLUBRIFORMIS IN SHEEP - THE EFFECT OF HOST AGE ON THE ESTABLISHMENT OF INFECTIVE LARVAE
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DOI：
10.1016/0020-7519(90)90151-c
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发表时间：
1990-05-01
影响因子：
4
通讯作者：
DONALD, AD
中科院分区：
文献类型：
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作者：
DOBSON, RJ;WALLER, PJ;DONALD, AD
在12-36周龄的无虫围栏中饲养的绵羊，每个工作日用2000个感染性T。colubriformis幼虫（L3）。在感染过程中的不同时间测量建立，发现对新感染的抗性的发展速度在老年人中比在年轻的宿主中更快。此外，逮捕的发展，在exsheathed L3阶段被发现是不太明显的老年人的主机。在围栏中暴露于与无蠕虫对应物相同的实验感染之前，在牧场上经历自然感染长达20周龄的绵羊表现出相似的免疫应答。然而，在36周龄时，牧场饲养的绵羊已经获得了对T。游蛇状的
Sheep, reared worm-free in pens and aged 12-36 weeks, were infected each weekday with 2000 infective T. colubriformis larvae (L3). Establishment was measured at various times during the course of infection and the rate of development of resistance to new infection was found to be faster in older than in younger hosts. In addition arrested development at the exsheathed L3 stage as found to be less marked in older hosts. Sheep which had experienced natural infection on pasture up to 20 weeks of age before exposure, in pens, to the same experimental infections as their worm-free counterparts showed similar immune responses. However, at 36 weeks of age, pasture-reared sheep had acquired a high level of resistance to infection with T. colubriformis.