Inhibition of proto-oncogene c-fos transcription by inhibitors of protein kinase C and ion transport.
Inhibition of proto-oncogene c-fos transcription by inhibitors of protein kinase C and ion transport.
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蛋白激酶 C 和离子转运抑制剂抑制原癌基因 c-fos 转录。
DOI：
10.1111/j.1432-1033.1987.tb10985.x
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发表时间：
1987
期刊：
影响因子：
--
通讯作者：
K. Nose
中科院分区：
文献类型：
--
作者：
M. Shibanuma;T. Kuroki;K. Nose
Both 4 beta-phorbol 12,13-didecanoate (PDD) and calcium ionophore A23187 induced c-fos mRNA accumulation with similar kinetics in human monocyte-like cells (U937). Their effects were additive. Cells pretreated with PDD were not induced to accumulate c-fos mRNA by PDD but remained responsive to the induction by A23187. Similarly cells pretreated with A23187 responded to PDD but not to A23187. Nuclear run-off transcription assay indicated that increase in the c-fos mRNA level after the second inducer treatment corresponded to transcriptional activation of the c-fos gene. The accumulation of c-fos mRNA and the transcriptional activation of c-fos induced by PDD or A23187 were inhibited by the protein kinase inhibitor H-7 and by quinidine and amiloride. The induction by A23187, but not that by PDD, was also inhibited by 4-aminopyridine, or tetraethylammonium. From these results, it is proposed that activation of protein kinase C and Na+ or K+ transport are required for c-fos induction caused by PDD and A23187.
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DOI：
10.1016/s0021-9258(17)38689-1
发表时间：
1985-11
期刊：
The Journal of biological chemistry
影响因子：
--
作者：
M. Greenberg;L. Greene;E. Ziff
通讯作者：
M. Greenberg;L. Greene;E. Ziff
影响因子：
--
作者：
Diamond, L;O'Brien, T G;Baird, W M
通讯作者：
Baird, W M
培养成纤维细胞中 Na /H 交换的激活：佛波酯、Ca2 离子载体和生长因子之间的协同和拮抗作用。
DOI：
10.1073/pnas.82.23.8053
发表时间：
1985
影响因子：
11.1
作者：
Vicentini,LM;Villereal,ML
通讯作者：
Villereal,ML
人结肠上皮细胞系中的环 AMP 和 Ca2 激活 K 转运。
DOI：
--
发表时间：
1985
期刊：
The Journal of biological chemistry
影响因子：
--
作者：
McRoberts,JA;Beuerlein,G;Dharmsathaphorn,K
通讯作者：
Dharmsathaphorn,K
肿瘤启动子对纤溶酶原激活剂基因表达的诱导和脱敏。
DOI：
--
发表时间：
1985
期刊：
The Journal of biological chemistry
影响因子：
--
作者：
Degen,JL;Estensen,RD;Nagamine,Y;Reich,E
通讯作者：
Reich,E