Directed ortho insertion (DoI): A new approach to functionalized aryl and heteroaryl zinc reagents
Directed ortho insertion (DoI): A new approach to functionalized aryl and heteroaryl zinc reagents
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DOI：
10.1021/ja074060h
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发表时间：
2007-10-17
影响因子：
15
通讯作者：
Knochel, Paul
中科院分区：
文献类型：
--
作者：
Boudet, Nadege;Sase, Shohei;Knochel, Paul
广泛的定向基团（酯、酮、乙酸、芳基磺酸盐、三氮烯、氨基甲酸酯）允许锌在LiCl存在下进行区域选择性定向邻位插入（DoI），从而产生多官能团芳基和杂芳基锌试剂。
A wide range of directing groups (ester, ketone, acetate, aryl sulfonate, triazene, carbamate) allow the regioselective directed ortho insertion (DoI) of zinc in the presence of LiCl leading to polyfunctional aryl and heteroaryl zinc reagents.