Copper Metal Organic Polyhedron (Cu-MOP) Hydrogel as Responsive Cytoprotective Shell for Living Cell Encapsulation
Copper Metal Organic Polyhedron (Cu-MOP) Hydrogel as Responsive Cytoprotective Shell for Living Cell Encapsulation
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铜金属有机多面体 (Cu-MOP) 水凝胶作为活细胞封装的响应性细胞保护壳
DOI：
10.1021/acsabm.0c00234
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发表时间：
2020-05-18
影响因子：
4.7
通讯作者：
Cao, Qiue
中科院分区：
文献类型：
--
作者：
Qin, Yu;Chen, Linlin;Cao, Qiue
铜金属有机多面体（Cu-MOP）水凝胶作为一种软壳材料，可以在物理和化学刺激下保护单细胞，在组织工程、细胞生物学和细胞器件等领域具有重要的应用前景。与以往的方法相比，该方法不仅具有更好的保护效果，而且制备和去除过程简单，对包埋细胞无损伤。
Single-cells coated with functional shells to protect them from external harsh condition have great potential applications in many fields such as tissue engineering, cell-based devices, cell biology, and so on. Herein, copper metal organic polyhedron (Cu-MOP) hydrogel has been applied as a soft shell for cell protection under both physical and chemical stimulations. Compared with a previous strategy, this MOP-Gel shell not only possesses more satisfied protection effect but also could be prepared and removed facilely without any damage to the encapsulated cells.