Epidemiology of reflux disease and CLE in East Asia.
Epidemiology of reflux disease and CLE in East Asia.
复制标题
东亚反流病和 CLE 的流行病学。
作者：
M. Hongo;T. Shoji
从文献调查中对反流性食管炎的地理发病率和时间发病率进行了研究，结果表明反流性食管炎的患病率似乎与经济发展有关。在东亚，反流性食管炎的患病率介于西欧和非洲之间。以幽门螺杆菌感染为参照，调查了东亚和仙台地区柱状内衬食道(CLE)的患病率。东亚和仙台的CLE患病率分别为0.9%和1.2%，幽门螺杆菌感染率分别为4%和20%。患者平均年龄为63岁，其中73%为男性。内窥镜下食管炎的严重程度较轻。在过去的25年里，食管腺癌在日本有所增加，但与鳞状细胞癌的比例很低，而且没有发现明显的变化。需要进一步观察，因为反流性食管炎在日本和东亚的患病率正在增加。
Geoprevalence and chronoprevalence of reflux esophagitis were studied from a literature survey, which showed that the prevalence of reflux esophagitis seems to be correlated with economical development. In East Asia, prevalence of reflux esophagitis is between that of Western Europe and Africa. The prevalence of columnar-lined esophagus (CLE) was surveyed in East Asia and in Sendai, with reference to Helicobacter pylori infection. Prevalence of CLE was 0.9% in East Asia and 1.2% in Sendai, and H. pylori infection was 4% and 20%, respectively. Patient mean age was 63 years, and 73% were male. Endoscopic severity of esophagitis was mild. Adenocarcinoma of the esophagus has increased in Japan in the past 25 years, but the ratio to squamous cell carcinoma is low and no significant changes have been identified. Further observation is required because the prevalence of reflux esophagitis is increasing in Japan and East Asia.