On-chip impedance measurements to monitor biofilm formation in the drinking water distribution network
On-chip impedance measurements to monitor biofilm formation in the drinking water distribution network
复制标题
用于监测饮用水分配网络中生物膜形成的片上阻抗测量
DOI：
10.1016/j.snb.2006.04.070
复制
发表时间：
2006
影响因子：
8.4
通讯作者：
J. Mas
中科院分区：
文献类型：
--
作者：
X. Muñoz‐Berbel;F. Muñoz;N. Vigués;J. Mas
水生微生物具有粘附在任何固体表面上的能力。当环境条件发生变化时，它们能够重新组织为生物膜，并将生命置于危险之中。生物膜允许细菌留在水管内而不被杀生物剂消灭。在其他特性中，生物膜是电绝缘的。正因为如此，当它们在金属换能器表面上生长时，生物膜产生电极-溶液界面性质的变化。这些变化已被监测使用阻抗测量和微芯片作为电换能器。生物膜的形成已经使用芯片上的金工作电极的特点和不同的生长阶段已涉及到特定的阻抗变化。采用新的和重复使用的芯片的细菌和非细菌的解决方案进行了测量。虽然已经发现新的和重复使用的芯片之间的差异，两种类型的电极可以用来评估生物膜的形成。还研究了几种杀菌剂对生物膜的影响。比较了过氧化物、强酸/强碱和醇类的消毒性能以及它们从芯片表面去除粘附物质的能力。
Aquatic microorganisms have the ability to adhere onto any solid surface. They are able to re-organise as biofilms when environmental conditions change and put their life at risk. Biofilms allow bacteria to remain inside water pipes without being eliminated by biocides. Among other properties, biofilms are electrically insulating. Because of this, as they grow on a metal transducer surface, biofilms produce changes in the electrode–solution interface properties. These changes have been monitored using impedance measurements and microchips as electrical transducers. Biofilm formation has been characterised using on-chip gold working electrodes and the various growth phases have been related to specific impedance changes. Measurements employing new and reused chips of bacterial and non-bacterial solutions have been performed. Although differences between new and reused chips have been found, both kinds of electrodes can be used to evaluate biofilm formation. The effect of several biocides on biofilms has also been studied. The disinfecting properties of peroxides, strong acid/bases and alcohols have been compared as well as their ability to remove adhered substances from chip surfaces.