A single test procedure to diagnose gestational diabetes mellitus
A single test procedure to diagnose gestational diabetes mellitus
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DOI：
10.1007/s00592-008-0060-9
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发表时间：
2009-03-01
影响因子：
3.8
通讯作者：
Seshiah, V.
中科院分区：
文献类型：
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作者：
Anjalakshi, C.;Balaji, V.;Seshiah, V.
妊娠期糖尿病（GDM）的普遍筛查，发现更多的病例，改善母亲和后代的预后。在所有的筛查测试中，世界卫生组织（WHO）的程序简单且具有成本效益;唯一的缺点是孕妇必须在空腹状态下接受口服葡萄糖耐量测试（OGTT）。因此，我们进行了一项研究，以阐明一个测试，是偶然的和可靠的诊断GDM。共800例孕妇进行了75克葡萄糖激发试验（GCT），无论最后一顿饭的时间和他们的2小时血糖（PG）估计。72 h后进行WHO推荐的2 h 75 g OGTT。GCT和WHO OGTT对GDM的诊断无统计学差异。总之，无论最后一餐的时间进行GCT是一个病人友好的方法，并导致最少的干扰孕妇的日常活动。
Universal screening for gestational diabetes mellitus (GDM), detects more cases and improves maternal and offspring prognosis. Of all the screening tests, World Health Organization (WHO) procedure is simple and cost effective; the only disadvantage is that the pregnant woman has to come in the fasting state to undergo oral glucose tolerance test (OGTT). Hence, we undertook a study to elucidate a test that is casual and reliable to diagnose GDM. A total of 800 pregnant women underwent 75-g glucose challenge test (GCT) irrespective of the time of the last meal and their 2-h plasma glucose (PG) was estimated. They also underwent a 2-h 75-g OGTT recommended by WHO after 72 h. There was no statistically significant difference in the glycemic profile between GCT and WHO OGTT in the diagnosis of GDM. In conclusion, GCT performed irrespective of the last meal timing is a patient-friendly approach and causes least disturbance in the pregnant woman's routine activities.