Cognitive Frailty Mechanisms, Tools to Measure, Prevention and Controversy (Retracted Article)
Cognitive Frailty Mechanisms, Tools to Measure, Prevention and Controversy (Retracted Article)
复制标题
DOI：
10.1016/j.cger.2017.03.001
复制
发表时间：
2017-08-01
影响因子：
3.3
通讯作者：
Vellas, Bruno
中科院分区：
文献类型：
--
作者：
Fougere, Bertrand;Delrieu, Julien;Vellas, Bruno
身体虚弱通常与认知障碍有关，可能是因为共同的潜在病理生理机制。为了促进这一领域的研究，人们提出了认知脆弱的概念，强调了大脑老化的重要作用。认知脆弱的定义是身体虚弱的老年人在没有痴呆症的情况下存在认知缺陷。这一亚型的虚弱被认为是重要的，因为它可能代表神经退行性疾病的前驱阶段，并可能是一种合适的。早期干预的目标。本报告的目的是完善认知脆弱性的定义和机制以及相关筛查工具的框架。
Physical frailty is often associated with cognitive impairment, possibly because of common underlying pathophysiologic mechanisms. To stimulate research in this field, the concept cognitive frailty was proposed, emphasizing the important role of brain aging. Cognitive frailty was defined as the presence of cognitive deficits in physically frail older persons without dementia. This subtype of frailty is deemed important, as it may represent a prodromal phase for neurodegenerative diseases and is potentially a suitable. target for early intervention. The aim of this report is to refine the framework for the definition and mechanisms of cognitive frailty and relevant screening tools.