The sound of blood: photoacoustic imaging in blood analysis
The sound of blood: photoacoustic imaging in blood analysis
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DOI：
10.1016/j.medntd.2023.100219
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发表时间：
2023-03
影响因子：
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通讯作者：
M. Veverka;Luca Menozzi;Junjie Yao
中科院分区：
文献类型：
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作者：
M. Veverka;Luca Menozzi;Junjie Yao
血液分析是现代医学的一个普遍而重要的方面。分析血液样本需要侵入性技术，各种测试系统，并且样本仅限于相对较小的体积。光声成像（派）是一种利用非电离能量的新型成像方式，有望成为当前方法的替代品。本文综述了派在血液分析中的临床应用。此外，我们还讨论了实施的障碍和克服这些挑战的未来方向。首先，我们讨论了血液细胞分析的三个应用：镰状细胞，细菌和循环肿瘤细胞检测。然后，我们讨论了应用程序的血浆分析，包括葡萄糖检测和抗凝定量。因此，我们希望这篇文章能为派在血液分析中的潜在应用提供启发，并促进进一步的研究，最终将派应用于临床实践。
Blood analysis is a ubiquitous and critical aspect of modern medicine. Analyzing blood samples requires invasive techniques, various testing systems, and samples are limited to relatively small volumes. Photoacoustic imaging (PAI) is a novel imaging modality that utilizes non-ionizing energy that shows promise as an alternative to current methods. This paper seeks to review current applications of PAI in blood analysis for clinical use. Furthermore, we discuss obstacles to implementation and future directions to overcome these challenges. Firstly, we discuss three applications to cellular analysis of blood: sickle cell, bacteria, and circulating tumor cell detection. We then discuss applications to the analysis of blood plasma, including glucose detection and anticoagulation quantification. As such, we hope this article will serve as inspiration for PAI's potential application in blood analysis and prompt further studies to ultimately implement PAI into clinical practice.