Continued high risk behaviors in HIV infected drug abusers
Continued high risk behaviors in HIV infected drug abusers
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DOI：
10.1300/j069v21n04_07
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发表时间：
2002-01-01
影响因子：
2.3
通讯作者：
Shor-Posner, G
中科院分区：
文献类型：
--
作者：
Miguez-Burbano, MJ;Pineda-Medina, L;Shor-Posner, G
为了描述艾滋病毒药物滥用者在高效抗逆转录病毒治疗（HAART）时代的当前危险行为，获得了社会人口统计学，医疗和行为信息，并确定了免疫测量。高风险性行为十分普遍。1995年之前诊断的参与者与HIV+伴侣发生无保护性行为的可能性是后来诊断的参与者的6倍（p = 0.05），使用污染针头的可能性是11倍（p = 0.05）。只有7%的人报告说坚持使用避孕套。许多（43%）参与者报告有多个HIV+和HIV-并发伴侣。大多数（65%），特别是女性（OR = 3，p = 0.02），这样做是为了毒品或金钱。尽管可检测到病毒载量，36%的人报告了无保护的肛交。与未接受治疗的男性相比，接受抗逆转录病毒治疗的男性倾向于无保护的肛交（OR = 2，p = 0.07）。艾滋病毒吸毒者，特别是1995年前确诊和/或接受抗逆转录病毒治疗的吸毒者的高危行为持续存在，表明迫切需要新的公共卫生战略。
To characterize current risk behaviors of HIV drug abusers in the highly active antiretroviral therapy (HAART) era, socio-demographic, medical and behavioral information were obtained and immune measurements determined. High-risk sexual practices were prevalent. Participants diagnosed before 1995 were 6 times more likely to have unprotected sex with HIV+ partners (p = 0.05) and 11 times more likely to use contaminated needles (p = 0.05) than participants with later diagnosis. Consistent condom use was reported by only 7% of the cohort. Many (43%) of the participants reported multiple HIV+ and HIV- concurrent partners. Most (65%), particularly women (OR = 3, p = 0.02), did so for drugs or money. Despite detectable viral loads, 36% reported unprotected anal sex. Antiretroviral-treated men, compared to non-treated, tended to have unprotected anal sex (OR = 2, p = 0.07). The continued high-risk behaviors of HIV drug users, particularly those diagnosed before 1995 and/or on antiretroviral therapy, indicates an urgent need for new public health strategies.