Cutaneous Lesions in Severe Combined Immunodeficiency: Two Case Reports and a Review of the Literature
Cutaneous Lesions in Severe Combined Immunodeficiency: Two Case Reports and a Review of the Literature
复制标题
严重联合免疫缺陷的皮肤病变：两例病例报告及文献综述
作者：
C. Llorente;J. Amoros;F. O. Frutos;J. R. Regueiro;R. L. Martin;A. Tapia;L. I. Díez
Abstract: Two patients with severe combined immunodeficiency (SCID) in whom cutaneous lesions were the first clinical feature were studied. Neither the morphology nor the histology of the lesions was uniform, although we have noted some common findings that can, in subsequent cases, lead us to suspect SCID. The immunologic defects were not uniform, representing the two poles of the spectrum of SCID. We believe that early recognition of the skin lesions is very important, since the patient's life expectancy can be increased by a bone marrow transplantation (1).
患有 Omenn 综合征的近交系中 T 淋巴细胞亚群的不平衡。
DOI：
10.1016/0090-1229(83)90093-4
发表时间：
1983
期刊：
Clinical immunology and immunopathology
影响因子：
--
作者：
Karol,RA;Eng,J;Cooper,JB;Dennison,DK;Sawyer,MK;Lawrence,EC;Marcus,DM;Shearer,WT
通讯作者：
Shearer,WT
T 细胞受体-CD3 复合物表面表达的家族性缺陷。
DOI：
10.1056/nejm198811033191806
发表时间：
1988
期刊：
The New England journal of medicine
影响因子：
--
作者：
Alarcon,B;Regueiro,JR;Arnaiz-Villena,A;Terhorst,C
通讯作者：
Terhorst,C
用于治疗严重联合免疫缺陷的 T 淋巴细胞耗尽的 HLA 单倍型不匹配骨髓移植后的重建。
DOI：
10.1073/pnas.79.19.6047
发表时间：
1982
影响因子：
11.1
作者：
Reinherz,EL;Geha,R;Rappeport,JM;Wilson,M;Penta,AC;Hussey,RE;Fitzgerald,KA;Daley,JF;Levine,H;Rosen,FS;Schlossman,SF
通讯作者：
Schlossman,SF