NASOPHARYNGEAL CARRIAGE OF BACTERIA IN OTITIS-PRONE AND NON-OTITIS-PRONE CHILDREN IN DAY-CARE-CENTERS
NASOPHARYNGEAL CARRIAGE OF BACTERIA IN OTITIS-PRONE AND NON-OTITIS-PRONE CHILDREN IN DAY-CARE-CENTERS
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DOI：
10.3109/00016488409107572
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发表时间：
1984-01-01
影响因子：
1.4
通讯作者：
ROSEN, C
中科院分区：
文献类型：
--
作者：
PRELLNER, K;CHRISTENSEN, P;ROSEN, C
在两年的时间里，每月定期以及在急性中耳炎（AOM）发作时从日托中心的儿童群体中采集鼻咽标本。肺炎球菌的携带率。将 26 名无症状和 AOM 发作时易患中耳炎 (OP) 儿童中的流感嗜血杆菌和卡他菌与 36 名非易患中耳炎 (NOP) 儿童的携带率进行比较。肺炎球菌、流感嗜血杆菌和卡他杆菌在 NOP 中的发现频率与无症状 OP 儿童中的频率相同。在 AOM 事件中，仅发现粘膜炎伯克氏菌，其频率明显高于预定培养中的频率。 6 种最常见分离的肺炎球菌类型/组（6、23、19、14、11、18）在定期从 NOP 和 OP 儿童中采集的培养物以及在 AOM 发作时采集的培养物中的频率相似。与 NOP 儿童相比，3 至 4 岁儿童中分离出流感嗜血杆菌和卡他菌的频率低于 2 至 3 岁无症状 OP 儿童。鼻咽部存在肺炎球菌、流感嗜血杆菌或卡他巴氏杆菌本身并不增加发生 AOM 的风险。
During a 2-yr period nasopharyngeal specimens were taken monthly on scheduled occasions as well as at episodes of acute otitis media (AOM) from a population of children attending day-care centers. The carriage rates of pneumococci. Haemophilus influenzae and Branhamella catarrhalis in 26 otitis-prone (OP) children when asymptomatic and at episodes of AOM were compared with the carriage rates in 36 non-otitis-prone (NOP) children. Pneumococci, H. influenzae and B. catarrhalis were found as frequently in NOP as in asymptomatic OP children. At AOM episodes only B. catarrhalis was found significantly more often than in the scheduled cultures. The frequencies of the 6 most commonly isolated pneumococcal types/groups (6, 23, 19, 14, 11, 18) were similar in the cultures taken from NOP and OP children on scheduled occasions as well as in cultures taken at AOM episodes. In contrast to the NOP children H. influenzae and B. catarrhalis were isolated less frequently in the 3- to 4-yr-old than in the 2- to 3-yr-old asymptomatic OP children. The presence of pneumococci, H. influenzae or B. catarrhalis in the nasopharynx does not per se increase the risk for the development of AOM.