HYPOGLYCEMIC TRITERPENOID SAPONINS FROM BOUSSINGAULTIA-BASELLOIDES
HYPOGLYCEMIC TRITERPENOID SAPONINS FROM BOUSSINGAULTIA-BASELLOIDES
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DOI：
10.1139/v90-312
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发表时间：
1990-11-01
影响因子：
1.1
通讯作者：
RIGUERA, R
中科院分区：
文献类型：
--
作者：
ESPADA, A;RODRIGUEZ, J;RIGUERA, R
New saponins with hypoglucaemic activity (1-4) and momordin Ic (5) have been isolated from the methanolic extract of the leaves of Boussingaultia baselloides. They were shown by spectroscopy and chemical transformation to be derivatives of 12,20(29)-dien-30-noroleanic acid. Boussingoside A1 (1) exhibits very strong hypoglucemic activity in rats. Acid hydrolysis of the saponin 1 yielded five transformation products (6-10), though one of them (larreagenin A (6), which has been reported in the literature as a genuine plant metabolite) is considered to be an artifact formed by the acid treatment.
