Salicylic acids as readily available starting materials for the synthesis of meta-substituted biaryls.
Salicylic acids as readily available starting materials for the synthesis of meta-substituted biaryls.
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DOI：
10.1039/c4cc09674f
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发表时间：
2015-02
影响因子：
4.9
通讯作者：
Junfei Luo;S. Preciado;Igor Larrosa
中科院分区：
文献类型：
--
作者：
Junfei Luo;S. Preciado;Igor Larrosa
水杨酸被证明是容易获得的和多用途的起始材料，其容易在Pd催化下经历串联芳基化-原脱羧过程。相应的间位芳基酚随后可以容易地转化为各种间位官能化的联芳基，突出了这种方法的多功能性，以获得这种结构基序。
Salicylic acids are shown to be readily available and versatile starting materials that easily undergo a tandem arylation-protodecarboxylation process under Pd-catalysis. The corresponding meta-arylphenols can subsequently be easily transformed into a variety of meta-functionalized biaryls, highlighting the versatility of this approach to access this structural motif.