Validity of dementia diagnoses in the Danish hospital registers
Validity of dementia diagnoses in the Danish hospital registers
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DOI：
10.1159/000107084
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发表时间：
2007-01-01
影响因子：
2.4
通讯作者：
Waldemar, Gunhild
中科院分区：
文献类型：
--
作者：
Phung, Thien Kieu Thi;Andersen, Birgitte Bo;Waldemar, Gunhild
背景资料：在丹麦全国医院登记的痴呆症诊断的有效性进行了评估，以确定这些登记在流行病学研究有关痴呆症的价值。研究方法：从2003年最后6个月首次登记的4，682名痴呆症诊断患者中随机选择了200名患者。对患者的医学杂志进行了审查，以评估他们是否符合ICD-10和/或DSM-IV痴呆和特定痴呆亚型的标准。2006年还活着的病人被邀请参加一次采访。结果：197种期刊可供审查，51例患者接受了采访。169例（85.8%）患者的痴呆症诊断正确。关于痴呆亚型，登记和验证过程的结果之间的一致性程度较低，Kappa值为0.36（95% CI 0.24-0.48）。结论：丹麦医院登记的痴呆综合征的有效性很高，可以进行有关痴呆的流行病学研究。阿尔茨海默氏病，虽然登记不足，也有一个很好的有效性，一旦诊断登记。一般而言，其他ICD-10痴呆亚型的登记有效性较低，不太适合流行病学研究。
Background: The validity of dementia diagnoses in the Danish nationwide hospital registers was evaluated to determine the value of these registers in epidemiological research about dementia. Methods: Two hundred patients were randomly selected from 4,682 patients registered for the first time with a dementia diagnosis in the last 6 months of 2003. The patients' medical journals were reviewed to evaluate if they fulfilled ICD-10 and/or DSM-IV criteria for dementia and specific dementia subtypes. The patients who were still alive in 2006 were invited to an interview. Results: One hundred and ninety-seven journals were available for review and 51 patients were interviewed. A registered diagnosis of dementia was found to be correct in 169 (85.8%) cases. Regarding dementia subtypes, the degree of agreement between the registers and the results of the validating process was low with a kappa of 0.36 (95% Cl 0.24-0.48). Conclusion: The validity of dementia syndrome in the Danish hospital registers was high and allows for epidemiological studies about dementia. Alzheimer's disease, although underregistered, also had a good validity once the diagnosis was registered. In general, other ICD-10 dementia subtypes in the registers had a low validity and are less suitable for epidemiological research.