Atypical visual change processing in children with autism: An electrophysiological Study
Atypical visual change processing in children with autism: An electrophysiological Study
复制标题
DOI：
10.1111/psyp.12006
复制
发表时间：
2013-03-01
期刊：
影响因子：
3.7
通讯作者：
Gomot, Marie
中科院分区：
文献类型：
--
作者：
Clery, Helen;Bonnet-Brilhault, Frederique;Gomot, Marie
自闭症谱系障碍（ASD）儿童可能会表现出非典型行为，以应对所有感觉方式发生的无人值守的变化。通过对失匹配负波（MMN）的分析，发现ASD存在非典型的自动听觉变化加工。本研究调查了ASD儿童的视觉偏差检测，以确定是否在其他感觉方式中对变化的异常反应。12名ASD儿童采用动态刺激的被动视觉oddball范式。与对照组相比，ASD儿童表现出更早的视觉失配反应，表明对视觉偏差的超敏反应。因此，这项研究与自闭症谱系障碍儿童存在一般非典型变化检测处理的假设一致，这可能导致他们对变化的不耐受。
Children with Autism Spectrum Disorder (ASD) may display atypical behaviors in reaction to unattended changes that occur in all sensory modalities. Atypical automatic auditory change processing has been highlighted in ASD via the analysis of mismatch negativity (MMN). The present study investigated visual deviancy detection in children with ASD in order to determine whether unusual reactions to change operate in other sensory modalities. Twelve children with ASD were presented with a passive visual oddball paradigm using dynamic stimuli. Compared to controls, children with ASD showed an earlier visual mismatch response, suggesting a hypersensitivity to visual deviancy. This study is thus consistent with the hypothesis of the existence of general atypical change detection processing in children with ASD that might contribute to their intolerance of change.