Response variability and timing precision of neuronal spike trains in vivo
Response variability and timing precision of neuronal spike trains in vivo
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DOI：
10.1152/jn.1997.77.5.2836
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发表时间：
1997-05-01
影响因子：
2.5
通讯作者：
Kaplan, E
中科院分区：
文献类型：
--
作者：
Reich, DS;Victor, JD;Kaplan, E
我们报告说，神经元的尖峰列车可以表现出很高的，刺激依赖的时间精度，即使在审判到审判的反应的变化，在几个传统的方式来衡量，仍然基本上独立的刺激。我们发现，视网膜神经节细胞和神经元的外侧膝状体核（LGN）的猫在体内显示这两个方面的发射行为，这是以前报道的矛盾。我们开发了一个简单的模型，将神经元视为“泄漏”的集成和发射设备，并表明它也可以表现出这两种行为。我们认为我们的研究结果的神经编码的问题的影响。
We report that neuronal spike trains can exhibit high, stimulus-dependent temporal precision even while the trial-to-trial response variability, measured in several traditional ways, remains substantially independent of the stimulus. We show that retinal ganglion cells and neurons in the lateral geniculate nucleus (LGN) of cats in vivo display both these aspects of firing behavior, which have previously been reported to be contradictory. We develop a simple model that treats neurons as ''leaky'' integrate-and-fire devices and show that it, too, can exhibit both behaviors. We consider the implications of our findings for the problem of neural coding.