A note upon the faradic stimulation of the postcentral gyrus in conscious patients.
A note upon the faradic stimulation of the postcentral gyrus in conscious patients.
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DOI：
10.1093/brain/32.1.44
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发表时间：
1909-01-01
期刊：
影响因子：
14.5
通讯作者：
Cushing, H
中科院分区：
文献类型：
--
作者：
Cushing, H
在我们朝着更准确的大脑皮层功能定位前进的过程中，最重要的步骤之一是采取了单极辐射的方法，谢林顿和格伦鲍尼准确地描绘了所谓的运动区的范围。他们将类人猿大脑皮质的这种可电兴奋的条带划分到中央裂(Bolandi)前壁和中央前回的毗邻表面，这一界限已通过最近的髓鞘形成研究和对皮质更精细的组织学的研究得到证实，这些研究表明，这一区域与Betz细胞的分布相对应。此外，谢林顿和格伦鲍恩对类人脑的观察后来被克劳斯和弗雷泽证实为人类；我自己也有机会刺激了50多名麻醉患者的大脑皮层，结果与汤普森·耶茨生理学实验室1901年报告的结果完全一致。这令人惊讶地将以前被认为是宽广的区域划分为相对狭窄的中央前条带，留下了芒克感觉运动场的很大一部分--其他人的旧“运动区”--位于中央裂隙的后面。关于这个磁场的功能--电流强度过大可能会引起运动--的猜测自然而然地出现了，而关于它是感官终点站的假设得到了某些组织学研究(特别是阿尔弗雷德·W·坎贝尔的研究)以及一些仔细观察的临床病例的支持。2.
ONE of the most important steps in our progress toward a more exact localization of function in the cerebral cortex was taken when, by a method of unipolar faradization, Sherrington and Grunbauni accurately delineated the confines of the so-called motor area. Their circumscription of this electrically excitable strip of cortex in the ape to the anterior wall of the fissura centralis (Bolandi) and to the adjoining surface of the precentral gyrus, has received confirmation through the more recent studies of myelinization, and through investigations into the finer histology of the cortex, which have shown that this area corresponds with the distribution of the Betz cells. Sherrington and Grunbaurn's observations on the anthropoid brain, furthermore, have since been confirmed for man by Krause and Frazier; and I have had the occasion myself to1 stimulate the cortex of more than fifty anesthetized patients with results in exact accord with those reported in 1901 from the Thompson Yates Laboratory of Physiology.This surprising delimitation of what had previously been considered a wide territory to a relatively narrow precentral strip, left, without definitely proven function, the large portion of Munk's sensori-motor field—the old" motor area" of others—lying posterior to the central fissure. Conjectures have naturally arisen in regard to the function of this field—one from which motion may be elicited by undue strength of current—and the presumption that it is a sensory end-station has received support from certain histological studies (notably those of Alfred W. Campbell) as well as from a number of carefully observed clinical cases. 2