Physical activity influences heart rate variability and very-low-frequency components in Holter electrocardiograms
Physical activity influences heart rate variability and very-low-frequency components in Holter electrocardiograms
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DOI：
10.1016/0008-6363(96)00081-8
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发表时间：
1996-08-01
影响因子：
10.8
通讯作者：
Sleight, P
中科院分区：
文献类型：
--
作者：
Bernardi, L;Valle, F;Sleight, P
目的：在长期记录中，RR间期变异性的主要部分是由于缓慢（< 0.03 Hz）波动，这似乎是心肌梗死后存活率的良好预测因素，其起源尚不清楚。方法：通过对10名健康人（年龄28岁[s.e.]）的RR间期进行频谱分析，以研究体力活动的影响。2]年），分别在休息（无活动）、交替休息和轻度运动（节律性活动）以及正常自发（随机）活动的1小时周期内进行。结果如下：与休息时相比，在随机和节律活动期间，由于功率低于0.03 Hz（从3017[467]到9606[966] ms（2））的增加，RR方差显著增加（从5802[1030]到13 388[1448] ms（2），P <0.05，到24959[2901]，P < 0.001）。P <0.001），分别解释总RR变异的55.4%、73.2%和86.1%。结论：RR变异性的大小及其较慢的波动在很大程度上取决于身体活动，无论其是否定期发生。因此，根据RR波动预测心血管预后的尝试应考虑体力活动的混杂效应，因为健康的受试者可能更活跃。
Objective: A major proportion of RR interval variability in long-term recordings is due to slow (< 0.03 Hz) fluctuations, which seem to be a good predictor of survival after myocardial infarction, whose origin remains unclear. Methods: To study the effect of physical activity we compared by spectral analysis of the RR interval in 10 healthy human subjects (aged 28[s.e. 2] years) during 1-h periods each of rest (no activity), alternating rest and mild exercise (rhythmic activity), and normal spontaneous (random) activity. Results: Compared to rest, during both random and rhythmic activities, the RR variance increased significantly (from 5802[1030] to 13 388[1448] ms(2), P < 0.05, and to 24959[2901], P < 0.001) due to an increase in power below 0.03 Hz (from 3017[467] to 9606[966] ms(2). P < 0.01, and to 21 103[2298] ms(2), P < 0.001) which explained 55.4, 73.2 and 86.1% of total RR variance, respectively. Conclusions: The amount of RR variability and its slower fluctuations largely depend on physical activity, regardless of its regular or irregular occurrence. Attempts to predict cardiovascular prognosis on the basis of RR fluctuations should therefore take account of the confounding effect of physical activity since healthier subjects would probably be more active.