IMPORTANT ISSUES IN THE DRUG-TREATMENT OF SCHIZOPHRENIA

IMPORTANT ISSUES IN THE DRUG-TREATMENT OF SCHIZOPHRENIA
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DOI:
10.1093/schbul/6.1.70
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发表时间:
1980-01-01
影响因子:
6.6
通讯作者:
CHAN, C
CHAN, C
中科院分区:
医学1区
文献类型:
--
作者:
DAVIS, JM;SCHAFFER, CB;CHAN, C

文献摘要

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大量的研究表明,抗精神病药物在治疗急性精神分裂症的有效性进行了选择性审查。评估与以下问题相关的研究证据:选择性治疗的适应症;药物应答者和无应答者的特征;高剂量吩噻嗪治疗的适应症;维持治疗的适应症;抗精神病药物的获益和风险。提出了有关精神药理学研究领域需要进一步发展的建议。
The large body of research demonstrating the effectiveness of antipsychotic drugs in the treatment of acute schizophrenia is selectively reviewed. Research evidence relevant to the following issues is assessed; indications for selective treatment; characteristics of drug responders and nonresponders; indications for high dosage phenothiazine treatment; indications for maintenance therapy; benefits and risks of antipsychotic drugs. Recommendations are made concerning areas of psychopharmacologic research that require further development.