First Total Synthesis of Isopsoralenoside
First Total Synthesis of Isopsoralenoside
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DOI：
10.2174/1570178619666220111115718
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发表时间：
2022
期刊：
影响因子：
--
通讯作者：
Hongbo Dong
中科院分区：
文献类型：
--
作者：
Min Wu;Lijia Xu;Mingwei Song;Ying Li;Yingying Wang;Hongbo Dong
Abstract:.The first total synthesis of the natural product iopsoralenoside, isolated from the n-butyl alcohol extract of Fructus Psoraleae (FP), was achieved in 17% yield over 7 steps. The key steps of the process are the glycosylation and irradiation promoted by ultraviolet light. This synthesis provides a sufficient amount of synthesized trans- and cis-isopsoralenoside for further bioassays.
