EXPERIMENTAL LONG-TERM STUDY OF TITANIUM IONS ELUTED FROM PURE TITANIUM MINIPLATES
EXPERIMENTAL LONG-TERM STUDY OF TITANIUM IONS ELUTED FROM PURE TITANIUM MINIPLATES
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DOI：
10.1002/jbm.820290716
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发表时间：
1995-07-01
期刊：
影响因子：
--
通讯作者：
IIZUKA, T
中科院分区：
文献类型：
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作者：
BESSHO, K;FUJIMURA, K;IIZUKA, T
对临床广泛使用的钛微型接骨板进行了长期研究，以阐明其作为永久固定器械的有效性。我们通过扫描电子显微镜检查了日本白色家兔的取出接骨板的表面和钛在器官中的积聚。植入两年后，钛板仅轻微腐蚀。此外，在器官中观察到明显的钛蓄积，尤其是在肺部。而左侧下颌骨间造口骨折动物的器官中钛的积累在植入后3个月最高，然后在2年内逐渐下降。钛微型接骨板最近已在临床上用于人体，尚未报告不良反应。目前的研究结果表明，使用钛微型板作为永久固定装置。(C)1995年，John Wiley and Sons，Inc.
A long-term study of titanium miniplates, which are in wide clinical use, was conducted to clarify their usefulness as a permanent fixing device. We examined by scanning electron microscopy the surfaces of removed plates and the accumulation of titanium in the organs of Japanese white rabbits. Two years after implantation the titanium plates were only slightly corroded. In addition, marked titanium accumulation was noted in the organs, especially in the lungs. However, the accumulation of titanium in the organs of animals with left distomolar mandibular fracture was highest at 3 months after implantation, and then gradually decreased over 2 years. Titanium miniplates have recently been used clinically in humans and no adverse reactions have yet been reported. The present findings suggest the use of titanium miniplates as permanent fixing devices. (C) 1995 John Wiley and Sons, Inc.