Quantification of the Radiographic Joint Space Width of the Ankle
Quantification of the Radiographic Joint Space Width of the Ankle
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DOI：
10.1007/s11999-009-0832-8
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发表时间：
2009-08-01
影响因子：
4.2
通讯作者：
Block, Joel A.
中科院分区：
文献类型：
--
作者：
Goker, Berna;Gonen, Emel;Block, Joel A.
脚踝关节间隙宽度的量化可以提供必要的信息，以评估潜在的疾病改良剂的效果和旨在改善腿部其他部位骨关节炎的装置的不良影响。目前的方法需要专有软件或没有得到很好的验证；我们的目的是开发和评估使用公共访问软件的数字关节空间宽度量化方法的可靠性。我们研究了95名患者，他们在踝关节没有症状，没有踝关节创伤史，但有症状的膝关节内侧骨关节炎，参与了一项正在进行的纵向试验。分别拍摄踝关节正位和仰卧位骨盆正位X线片，并用Image J软件(US NIH，Bethesda，MD)测量最窄的胫距内侧关节间隙宽度和髋关节间隙宽度。右、左踝内侧关节间隙宽度分别为2.56+/-A0.50和2.55+/-A0.48 mm，外侧关节间隙宽度分别为2.45+/-A0.55和2.44+/-A0.52 mm。同一观察者重复测量内、外侧关节间隙的变异系数分别为1.13%和4.5%，不同观察者重复测量的变异系数分别为7.30%和7.27%。考虑到身高，男性的关节间隙宽度比女性更宽。踝关节间隙宽度与髋关节间隙宽度、身高、体重相关，与年龄无关。
Quantification of joint space width of the ankle could provide information essential to evaluate the effects of potential disease-modifying agents and adverse effects of devices intended to ameliorate osteoarthritis elsewhere in the lower extremity. Current methods require proprietary software or have not been well validated; our purpose was to develop and assess the reliability of a digital joint space width quantification method using public access software. We studied 95 patients, asymptomatic in the ankles and without history of ankle trauma, but with symptomatic medial knee osteoarthritis, participating in an ongoing longitudinal trial. Weightbearing anteroposterior radiographs of the ankle and supine radiographs of the pelvis were assessed, and the narrowest medial and lateral tibiotalar joint space widths and hip joint space widths were measured using Image J software (US NIH, Bethesda, MD). Medial joint space widths were 2.56 +/- A 0.50 and 2.55 +/- A 0.48 mm, and lateral joint space widths were 2.45 +/- A 0.55 and 2.44 +/- A 0.52 mm, for right and left ankle, respectively. Coefficients of variation for repeat measurements by the same observer were 1.13% and 4.5%, and by different observers 7.30% and 7.27%, for medial and lateral joint space widths, respectively. Men had wider joint space widths than women when accounting for height. Joint space width of the ankle correlated with the joint space width of the hip and with height and weight, but not with age.