Digital cineradiographic study of swallowing in patients with amyotrophic lateral sclerosis
Digital cineradiographic study of swallowing in patients with amyotrophic lateral sclerosis
复制标题
DOI：
10.1007/s11547-007-0214-9
复制
发表时间：
2007-12-01
影响因子：
8.9
通讯作者：
Lagalla, R.
中科院分区：
文献类型：
--
作者：
Lo Re, G.;Galia, M.;Lagalla, R.
目的。本研究旨在评价数字电影摄影在肌萎缩侧索硬化症(ALS)吞咽障碍患者诊断中的应用价值，以期规划适当的治疗途径。从2005年1月到2006年9月，23名ALS患者(10名男性和13名女性；平均年龄41.3±8.6岁)接受了数字放射成像评估吞咽困难的分级。所有患者均采用Hillel ALS严重程度评分(ALSSS)进行分级。所有检查均在配备数字C臂的放射控制设备上进行。X线摄片技术使我们能够区分口腔(17/23)和/或咽部(19/23)吞咽障碍患者和无吞咽障碍患者(4/23)。14/23例患者吞咽时有造影剂进入上呼吸道，5/23例患者有造影剂吸入下呼吸道。视频透视吞咽研究在评估吞咽障碍方面具有很高的诊断能力，因为它能够确定损害的程度和原因。此外，这项研究被证明对计划语言治疗和ALS患者的随访很有用。
Purpose. This study was performed to evaluate the usefulness of digital cineradiography in detecting swallowing disorders in dysphagic patients affected by amyotrophic lateral sclerosis (ALS) with a view to planning an adequate therapeutic approach.Material and methods. From January 2005 to September 2006, 23 patients (10 men and 13 women; mean age 41.3 +/- 8.6 years) affected by ALS were evaluated with digital cineradiography to assess the grade of dysphagia. All patients were classified using the Hillel ALS Severity Scale (ALSSS). All examinations were performed with radiocontrolled equipment provided with a digital C-arm.Results. The cineradiographic technique enabled us to differentiate patients with disorders of the oral (17/23) and/or pharyngeal (19/23) swallowing phase from those without swallowing dysfunction (4/23). In 14/23 patients, passage of contrast medium into the upper airways was observed during swallowing, whereas in 5/23 cases, aspiration of contrast medium into the lower airways was recorded.Conclusions. The videofluoroscopic swallowing study has high diagnostic capabilities in the evaluation of swallowing disorders, as it is able to identify the degree and causes of impairment. In addition, the study proved useful for planning speech therapy and for follow-up in patients with ALS.