Two novel single nucleotide polymorphisms (SNPs) of the CYP2D6 gene in Japanese individuals.
Two novel single nucleotide polymorphisms (SNPs) of the CYP2D6 gene in Japanese individuals.
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DOI：
10.2133/dmpk.20.294
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发表时间：
2005-08-01
影响因子：
2.1
通讯作者：
Mizugaki, Michinao
中科院分区：
文献类型：
--
作者：
Ebisawa, Aiko;Hiratsuka, Masahiro;Mizugaki, Michinao
我们分析了来自286名日本人的CYP 2D 6基因的所有外显子和外显子-内含子连接。我们发现了两个新的单核苷酸多态性（SNPs），第5外显子2556 C>T（Thr 261 Ile）和第8外显子3835 A>C（Lys 404 Gln）。这两个SNP的频率均为0.002。
We analyzed all the exons and exon-intron junctions of the CYP2D6 gene from 286 Japanese individuals. We detected two novel single nucleotide polymorphisms (SNPs) 2556C>T in exon 5 (Thr261Ile) and 3835A>C in exon 8 (Lys404Gln). Both these SNPs showed a frequency of 0.002.