Roles of adsorbed film and gel layer in hydration lubrication for articular cartilage
Roles of adsorbed film and gel layer in hydration lubrication for articular cartilage
复制标题
DOI：
10.1243/13506501jet536
复制
发表时间：
2009-03
期刊：
影响因子：
--
通讯作者：
T. Murakami;K. Nakashima;Y. Sawae;N. Sakai;Natsuko Hosoda
中科院分区：
文献类型：
--
作者：
T. Murakami;K. Nakashima;Y. Sawae;N. Sakai;Natsuko Hosoda
摘要为了维持自然滑膜的低摩擦和低磨损，在局部直接接触的混合或边界润滑条件下，关节软骨表面形成的吸附膜似乎起着重要的作用。此外，位于关节软骨最表层的蛋白多糖凝胶层通过水化润滑机制在保持低摩擦和低磨损方面发挥了重要作用，即使在去除吸附薄膜后也是如此。然而，吸附膜与水化膜/表面之间的相互作用或协同作用尚未阐明。为了探讨关节软骨表面的吸附膜和凝胶层在水化润滑中的作用，在关节软骨与玻璃板的往复摩擦试验中，观察了反复摩擦，包括中断-卸载过程后重新启动时摩擦的变化。值得注意的是，在加载后立即重新启动时，水合润滑有望生效。根据有无表面凝胶层的实验结果，讨论了蛋白质吸附膜在水化润滑中的作用。结合凝胶层的存在，对白蛋白和γ球蛋白进行了比较。
Abstract To maintain low friction and low wear in natural synovial joints, adsorbed film formation on articular cartilage surface appears to play an important role in mixed or boundary lubrication regime where local direct contact occurs. Furthermore, the proteoglycan gel layer at the uppermost superficial zone in articular cartilage appears to play an important role in preserving low friction and low wear by the hydration lubrication mechanism even after removal of adsorbed film. However, the interaction or synergistic action between adsorbed film and hydrated film/surface has not yet been clarified. To examine the roles of adsorbed film and gel layer on articular cartilage surface in hydration lubrication, the changes in friction were observed in the reciprocating test of articular cartilage against a glass plate, at repeated rubbing including restarting after interrupting—unloading process. It is noticed that at restarting immediately after loading, hydration lubrication is expected to become effective. The lubricating roles of protein-adsorbed film in hydration lubrication are discussed on the basis of experimental results in both cases with and without surface gel layer. The comparison of albumin and γ -globulin is described in connection with the existence of a gel layer.