Heart and lung transplantation in the United States, 1997-2006
Heart and lung transplantation in the United States, 1997-2006
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DOI：
10.1111/j.1600-6143.2008.02175.x
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发表时间：
2008-01-01
影响因子：
8.8
通讯作者：
Murray, S.
中科院分区：
文献类型：
--
作者：
Mulligan, M. S.;Shearon, T. H.;Murray, S.
本文重点介绍了1997年至2006年期间心脏和肺移植的趋势，利用OPTN和SRTR的数据。在过去十年中，积极等待心脏移植的候选人总数下降了45%，从1997年的2414例下降到2006年的1327例。在同一时期，等待心脏移植的患者的总体死亡率有所下降。在1999年至2005年新的分类系统开始时，心脏移植时不同状态组之间的受体分布变化不大。心脏移植后第一年的死亡人数稳步下降。2006年底，有2885名候选人等待肺移植，比1997年增加了10%。在过去的十年中，上市患者的移植时间中位数下降了87%，从1997年的1053天下降到2006年的132天。自2005年5月实施新的肺分配系统以来，根据生存获益和紧迫性而不是等待时间，选择上市和移植的患者已经转向更紧迫的患者。2006年只有31例心肺移植手术，低于1997年的62例。
This article highlights trends in heart and lung transplantation between 1997 and 2006, drawing on data from the OPTN and SRTR. The total number of candidates actively awaiting heart transplantation declined by 45% over the last decade, dropping from 2414 patients in 1997 to 1327 patients in 2006. The overall death rates among patients awaiting heart transplantation declined over the same period. The distribution of recipients among the different status groups at the time of heart transplantation changed little between the inception of the new classification system in 1999 and 2005. Deaths in the first year after heart transplantation have steadily decreased. At the end of 2006, 2885 candidates were awaiting a lung transplant, up 10% from the 1997 count. The median time-to-transplant for listed patients decreased by 87% over the decade, dropping from 1053 days in 1997 to 132 days in 2006. Selection for listing and transplantation has shifted toward more urgent patients since the May 2005 implementation of a new lung allocation system based on survival benefit and urgency rather than waiting time. Only 31 heart-lung transplants were performed in 2006, down from a high of 62 in 1997.