Climate is associated with prevalence and severity of radiographic hand osteoarthritis
Climate is associated with prevalence and severity of radiographic hand osteoarthritis
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DOI：
10.1016/j.jchb.2011.04.003
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发表时间：
2011-01-01
影响因子：
0.6
通讯作者：
Kobyliansky, E.
中科院分区：
文献类型：
--
作者：
Kalichman, L.;Korosteshevsky, M.;Kobyliansky, E.
本研究的目的是评估地理位置和气候因素是否与放射性手骨关节炎（OA）的患病率和严重程度在几个样本的同一种族，总样本包括2079俄罗斯族（900名男性和1179名女性），属于7个样本来自不同的地理位置在前苏联。居住地的特点是纬度，经度，海拔和气候参数（平均温度，湿度，1月和7月的日照时间）。从每个个体获得左手的X线照片。根据Kellgren和Lawrence的分级系统，对14个手关节的骨关节炎（OA）进行了评价。骨性关节炎的特征是至少有一个受累关节，其严重程度是受累关节的数量（NAJ）。统计分析包括患病率估计、多项式和Logistic回归。方差分析和相关分析：手OA和NAJ的患病率与纬度和海拔高度以及大多数气候参数（除了季节间温度振幅和1月和7月平均气压）显著相关。手OA患病率与海拔高度（r = 0.29，p < 0.001）、年降水量（r =-0.26，p < 0.001）和7月平均气温（r = 0.26，p < 0.001）的相关性最高。NAJ与海拔高度的相关性最高（r = 0.51，p < 0.001），1月平均湿度（r =-0.44，p < 0.001）与1月平均日时数的关系（r = 0.0.37，p < 0.001）目前的研究表明，俄罗斯样本中放射学手OA的患病率和严重程度的差异很可能取决于居住地的气候条件。(C)2011年Elsevier GmbH。All rights reserved.
The aim of this study was to evaluate whether geographic location and climatic factors are associated with prevalence and severity of radiographic hand osteoarthritis (OA) in several samples of the same ethnicity.The total sample included 2079 ethnic Russians (900 males and 1179 females), belonging to 7 samples from different geographic locations in the former USSR. Places of residence were characterized by latitude, longitude, altitude and climatic parameters (mean temperatures, humidity, and daylight duration of January and July). Radiographs of the left hand were obtained from each individual. Osteoarthritis (OA) was evaluated in 14 hand joints according to Kellgren and Lawrence's grading system. OA was characterized by the presence of at least one affected joint and its severity by the number of affected joints (NAJ). Statistical analysis included prevalence estimation, polynomial and logistic regressions. ANOVA and correlation analyses.Prevalence of hand OA and NAJ were significantly associated with latitude and altitude and with most climatic parameters (except the inter-seasonal temperature amplitude and the mean atmospheric pressure of January and July). The highest correlations of hand OA prevalence were found with altitude (r = 0.29, p < 0.001), annual precipitation (r = -0.26, p < 0.001) and the mean temperatures of July (r = 0.26, p < 0.001). The highest correlations of NAJ were found with altitude (r = 0.51, p < 0.001), mean humidity in January (r = -0.44, p < 0.001) and the mean day duration in January (r = 0.0.37, p < 0.001).The present study demonstrates that the differences in prevalence and severity of radiographic hand OA among Russian samples are most likely dependent on climatic conditions in the place of residence. (C) 2011 Elsevier GmbH. All rights reserved.