Increased Right Frontal Brain Activity During the Mandarin Hearing-in-Noise Test.
Increased Right Frontal Brain Activity During the Mandarin Hearing-in-Noise Test.
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DOI：
10.3389/fnins.2020.614012
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发表时间：
2020
影响因子：
4.3
通讯作者：
Buckey JC
中科院分区：
文献类型：
--
作者：
Song F;Zhan Y;Ford JC;Cai DC;Fellows AM;Shan F;Song P;Chen G;Soli SD;Shi Y;Buckey JC
先前的研究表明，在背景噪音中进行言语理解时，额叶大脑的激活会增加。然而，很少有人使用声调语言。在使用声调语言进行具有挑战性的鼻子言语任务期间，大脑激活的正常模式仍不清楚。普通话噪声环境听力测试 (HINT) 是一项成熟的测试，用于评估在背景噪音中解读语音的能力。目前的研究使用普通话提示 (MHINT) 句子和功能磁共振成像 (fMRI) 来评估 MHINT 句子的大脑激活情况。招募了三十名以普通话为母语且周边听力正常的受试者。进行功能性 MRI 时，向受试者呈现具有低水平背景噪声 [信噪比 (SNR) = +3 dB] 的提示“清晰”句子或具有高水平背景噪声 (SNR = −5 dB) 的“嘈杂”句子。受试者被要求通过按下按钮来回答句子中是否包含视觉呈现的目标词。比较了嘈杂句子和清晰句子之间的大脑激活。每种条件下的激活也与静息、无句子呈现条件进行比较。嘈杂的句子理解显示与语调处理和工作记忆相关的区域的活动增加，包括右上回和中额回 [Brodmann Areas (BAs) 46, 10]。听觉、语言、记忆和体感区域的噪音活动减少，包括双侧颞上回和中回、左侧赫施尔回（BAs 21、22）、右侧颞极（BA 38）、双侧杏仁核-海马交界处和海马旁回（BAs 28、35）、左侧顶下小叶延伸至左侧中央后回（BAs） 2, 40)，以及左壳核。当理解嘈杂的普通话句子时，右半球的额叶激活会增加。与使用非声调语言的研究相比，这种激活是强烈的右侧激活，并且涉及先前未报道的子区域。这些发现可能反映了这种声调语言的词汇声调感知方面的额外努力。此外，这种连续功能磁共振成像协议可以提供一种省时的方法，通过具有挑战性的噪声中语音任务来评估大脑激活的群体差异。
Previous studies have revealed increased frontal brain activation during speech comprehension in background noise. Few, however, used tonal languages. The normal pattern of brain activation during a challenging speech-in-nose task using a tonal language remains unclear. The Mandarin Hearing-in-Noise Test (HINT) is a well-established test for assessing the ability to interpret speech in background noise. The current study used Mandarin HINT (MHINT) sentences and functional magnetic resonance imaging (fMRI) to assess brain activation with MHINT sentences. Thirty native Mandarin-speaking subjects with normal peripheral hearing were recruited. Functional MRI was performed while subjects were presented with either HINT “clear” sentences with low-level background noise [signal-to-noise ratio (SNR) = +3 dB] or “noisy” sentences with high-level background noise (SNR = −5 dB). Subjects were instructed to answer with a button press whether a visually presented target word was included in the sentence. Brain activation between noisy and clear sentences was compared. Activation in each condition was also compared to a resting, no sentence presentation, condition. Noisy sentence comprehension showed increased activity in areas associated with tone processing and working memory, including the right superior and middle frontal gyri [Brodmann Areas (BAs) 46, 10]. Reduced activity with noisy sentences was seen in auditory, language, memory and somatosensory areas, including the bilateral superior and middle temporal gyri, left Heschl’s gyrus (BAs 21, 22), right temporal pole (BA 38), bilateral amygdala-hippocampus junction, and parahippocampal gyrus (BAs 28, 35), left inferior parietal lobule extending to left postcentral gyrus (BAs 2, 40), and left putamen. Increased frontal activation in the right hemisphere occurred when comprehending noisy spoken sentences in Mandarin. Compared to studies using non-tonal languages, this activation was strongly right-sided and involved subregions not previously reported. These findings may reflect additional effort in lexical tone perception in this tonal language. Additionally, this continuous fMRI protocol may offer a time-efficient way to assess group differences in brain activation with a challenging speech-in-noise task.
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影响因子：
2.6
作者：
Xu, Guoqing;Zhang, Linjun;Li, Ping
通讯作者：
Li, Ping
影响因子：
3.7
作者：
Zhan, Yi;Fellows, Abigail M.;Buckey, Jay C.
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Buckey, Jay C.
影响因子：
5.7
作者：
Macey, PM;Macey, KE;Harper, RM
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Harper, RM
影响因子：
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作者：
Moore DR;Edmondson-Jones M;Dawes P;Fortnum H;McCormack A;Pierzycki RH;Munro KJ
通讯作者：
Munro KJ
影响因子：
3.2
作者：
Davis, Matthew H.;Ford, Michael A.;Johnsrude, Ingrid S.
通讯作者：
Johnsrude, Ingrid S.