Non‐disjunction in trisomy 21: study of chromosomal heteromorphisms in 110 families
Non‐disjunction in trisomy 21: study of chromosomal heteromorphisms in 110 families
复制标题
21三体不分离：110个家系的染色体异态性研究
DOI：
10.1111/j.1469-1809.1980.tb00942.x
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发表时间：
1980
影响因子：
1.9
通讯作者：
Aksel Lange
中科院分区：
文献类型：
--
作者：
M. Mikkelsen;H. Poulsen;JßRGEN Grinsted;Aksel Lange
QM variants on chromosome 21 and silver staining of NOR regions were applied in the study of non‐disjunction in 110 families from different parts of Denmark. In 76% of the families the study was informative. Paternal failures were observed in 11 % on Funen as compared 23.5% on Zealand. In one family, crossing‐over on the short arms of chromosome 21 in the mother and mitotic non‐disjunction of chromosome 21 was observed.
