Inonotolides A-C, isopimarane diterpenoid lactones from Inonotus sinensis
Inonotolides A-C, isopimarane diterpenoid lactones from Inonotus sinensis
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桦褐孔菌内酯 A-C，来自桦褐孔菌的异海葵烷二萜内酯
DOI：
10.1016/j.fitote.2018.04.006
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发表时间：
2018-06-01
期刊：
影响因子：
3.4
通讯作者：
Liu, Ji-Kai
中科院分区：
文献类型：
--
作者：
Ding, Jian-Hai;Li, Zheng-Hui;Liu, Ji-Kai
从担子菌中华绒孔菌（Inonotus sinensis）中分离得到三个新的异海松烷二萜内酯，命名为inonotolides A-C（1 ~ 3）。它们的结构在广泛的光谱研究的基础上被阐明，并且通过单晶X-射线晶体学分析证实了inonotrea A（1）的结构。评价了所有化合物对五种人癌细胞系的细胞毒性。
Three new isopimarane diterpenoid lactones, named inonotolides A-C (1 3), were isolated from cultures of the basidiomycete Inonotus sinensis. Their structures were elucidated on the basis of extensive spectroscopic studies and the structure of inonotolide A (1) was confirmed by single-crystal X-ray crystallographic analysis. All compounds were evaluated for their cytotoxicities against five human cancer cell lines.