Non-medical use of prescription drugs, polysubstance use, and mental health in transgender adults
Non-medical use of prescription drugs, polysubstance use, and mental health in transgender adults
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DOI：
10.1016/j.drugalcdep.2013.02.027
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发表时间：
2013-09-01
影响因子：
4.2
通讯作者：
Snipes, Daniel
中科院分区：
文献类型：
--
作者：
Benotsch, Eric G.;Zimmerman, Rick;Snipes, Daniel
工作背景：近年来，处方药的非医疗使用（NMUPD）急剧增加，并与不良健康结果相关。以前的工作没有检查这种行为在大样本的transgender adults.Methods：Transgender adults（N = 155）从社区场所在中大西洋地区招募完成匿名，自我管理的调查评估人口统计信息，NMUPD和其他物质的使用，激素的非医疗用途，心理社会因素，和精神症状。总体而言，26.5%的受试者报告了终生NMUPD，最常报告的非医学用药为处方镇痛药（23.9%）、抗焦虑药（17.4%）、兴奋剂（13.5%）和镇静剂（8.4%）。也经常报告激素的非医疗使用（30.3%）。报告NMUPD的参与者也更有可能报告使用非法药物。NMUPD，而不是激素的非医疗用途，与较低的自尊，更多的基于性别身份的歧视，以及更多的自我报告的焦虑，抑郁和躯体不适症状有关。在控制人口统计学因素和其他物质use.Conclusions：处方药滥用在这个样本中是相对常见的，并与情绪困扰的精神症状仍然与NMUPD统计相关。对这一人群的物质使用和心理健康干预可能会受益于NMUPD的评估和治疗。(C)2013爱思唯尔爱尔兰有限公司版权所有。
Background: In recent years, the non-medical use of prescription drugs (NMUPD) has increased dramatically and has been associated with adverse health outcomes. Prior work has not examined this behavior in large samples of transgender adults.Methods: Transgender adults (N = 155) recruited from community venues in the Mid-Atlantic region completed anonymous, self-administered surveys assessing demographic information, NMUPD and other substance use, the non-medical use of hormones, psychosocial factors, and psychiatric symptoms.Results: Overall, 26.5% of participants reported lifetime NMUPD with the most commonly reported medications used non-medically being prescription analgesics (23.9%), anxiolytics (17.4%), stimulants (13.5%), and sedatives (8.4%). Non-medical use of hormones was also frequently reported (30.3%). Participants reporting NMUPD were also more likely to report the use of illicit drugs. NMUPD, but not the non-medical use of hormones, was associated with lower self-esteem, more gender identity-based discrimination, and more self-reported symptoms of anxiety, depression, and somatic distress. Psychiatric symptoms remained statistically associated with NMUPD after controlling for demographic factors and other substance use.Conclusions: Prescription drug misuse was relatively common in this sample and was robustly associated with emotional distress. Substance use and mental health interventions for this population may benefit from incorporating the assessment and treatment of NMUPD. (C) 2013 Elsevier Ireland Ltd. All rights reserved.