Emergent Behaviors in a Deterministic Model of the Human Uterus
Emergent Behaviors in a Deterministic Model of the Human Uterus
复制标题
DOI：
10.1177/1933719110376544
复制
发表时间：
2010-10-01
影响因子：
2.9
通讯作者：
Simon, Carl
中科院分区：
文献类型：
--
作者：
Barclay, Mel;Andersen, H.;Simon, Carl
人类的出生过程是由子宫收缩提供动力的，子宫收缩具有依赖于肌肉活动生理学的可观察模式。我们探索了先前设计的模型（1）模拟子宫以评估整体收缩模式。该模型是一个元胞自动机，它从细胞相互作用和子宫几何形状的一些简单规则模拟子宫活动的复杂性。使用元胞自动机的多个实验涉及不同的子宫形状，细胞数量以及活性和静息细胞的初始分布。结果表明，复杂的收缩模式类似于在人类劳动中观察到的。在模拟中至少出现了两种行为模式，一种与有效劳动一致，另一种则不一致。细胞自动机的实验提供了对刻板和无序的劳动模式的见解，这些模式会在劳动没有进展的情况下产生患者的不适。我们推测，复杂的子宫收缩模式可能有其他的作用，在准备劳动和分娩。
The human birth process is powered by uterine contractions that have observable patterns that depend on the physiology of muscular activity. We explored a previously designed model(1) simulating the uterus to assess global contractile patterns. The model is a cellular automaton that simulates the complexities of uterine activity from a few simple rules of cellular interaction and uterine geometry. Multiple experiments using the cellular automaton involved different uterine shapes, cell numbers, and initial distributions of active and resting cells. Results demonstrate complex contraction patterns similar to those observed in human labor. At least 2 modes of behavior appear in the simulations, one consistent with effective labor and one not. Experiments with cellular automata provide insights into stereotypic and disordered labor patterns that produce patient discomfort without progress in labor. We hypothesize that complex uterine contraction patterns may have other roles in the preparation for labor and birth.